The Role of Chirality in Drug Design and Delivery: A Comprehensive Review

Introduction The rotation of plane-polarized light by chiral substances was first observed in 1812 by a French physicist Jean-Baptiste Biot. Chiral chemistry was discovered by Louis Pasteur, a French chemist & biologist, in 1848 by inventing 2 isomers of sodium potassium tartrate (Fig. 1). The term chirality was coined in 1894 by Lord Kelvin, a … Read more