Momordica charantia leaves extract has been studied of using using the antibacterial methods, disc diffusion methods, wound healing, and bone marrow micronucleus assay. The different concentrations had good antibacterial activity against different strains of bacteria in dose dose-dependent manner. It has also shown wound healing activity on the skin of Swiss mice. And it was greater than the positive control group. The micronucleus suppression in different doses was observed, and it showed a significant difference. The present study is important because the Momordica charantia plant is important. because it cures various ailments in traditional medicine.