CRISPR-Cas9 as a Curative Frontier: Precision Editing Strategies for Sickle Cell Disease
INTRODUCTION 1.1 Overview of Sickle Cell Anemia Despite decades of advancements in biomedicine, sickle cell anemia (SCA), one of the most researched monogenic illnesses, continues to be a significant health burden worldwide. The disorder is caused by a single A→T transversion in the HBB gene (rs334), which causes valine to replace glutamic acid at position … Read more