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Assessment of Anthelmintic Activity of Cinnamic Acid and Its Three Analogs: a Combined in Vitro and in Silico Study

  • Sheeba Baby Alex1,2
  • Ullas Mohan1
  • M. S.Latha2

INTRODUCTION Parasitic worms, known as helminths, are a significant source of public health concern due to their widespread occurrence in both human and animal populations, resulting in a high incidence of infection.Helminth infections are estimated to affect approximately a quarter of the world’s population.Helminths are unique among parasites because they multiply inside the definitive host … Read more

Understanding the Therapeutic Versatility of Apigenin and Quercetin: Broad Applications in Health and Wellness

  • Priya Shetti
  • Shivangini Singh
  • Vijay Kumbar
  • Suneel Dodamani
  • Ramesh Paranjape
  • Mitali Kubade

Introduction Flavonoids are quite an important class of natural substances. Specifically, these are a type of secondary metabolic by-products from crops that have a polyphenolic framework as well as are frequently found in vegetables, fruits, and some beverages [1]. These substances provide plants with adefense against diseases, UV rays, and herbivores [2]. Anthocyanins, flavones, flavanols, … Read more

Evaluation of antioxidant and antidiabetic properties of ethyl acetate fraction from Anacardium occidentale leaves, in-vitro and in-silico

  • Tajudeen Afolayan Lawal1
  • Chimaobi James Ononamadu1
  • Victoria Oluwabusayo Akinjoko1
  • Divine El-Nathan Segba1
  • Qazeem Oyeniyi Sholadoye2
  • Musa Bashir 3

Introduction Diabetes mellitus refers to a group of metabolic disorders that are characterized by elevated blood sugar levels. This condition can arise from either excessive glucose production or insufficient insulin secretion [1]. Diabetes is a chronic condition that currently has no known cure; however, it can be effectively managed through medication, a balanced diet, and … Read more

Green Synthesis of Silver, Copper and Bimetallic (Ag-Cu) Nanoparticle using Aqueous Extract of Achyranthes Aspera for Hepatoprotective activity on HEPG2 Cell lines against CCl4 induced toxicity

  • B Sirisha1,2
  • D Meera1
  • Ch. Venkatramana Devi1

According to the WHO, 21,000 plants reutilized for medicinal purposes worldwide, and India has a rich tradition of using medicinal herbs and spices. There are 2,500 species in India, while 150 of them are used extensively for economic purposes[1]. Day-by-day usage for plant-based medications is rising globally including in India[2].Due to the presence of phytochemicals, … Read more

Characterisation and Cytotoxic Evaluation of the Compound Obtained from Petroleum Ether Fraction of the Tuber Amorphophallus paeoniifolius

  • Latha M. S
  • Anju Alex

Cancer is a severe disease that has a significant impact on a global scale. It does not differentiate based on age or gender, although certain types of cancer are more common in one gender than the other.Roughly 95 percent of cancer cases are the result of genetic mutations driven by environmental and lifestyle factors, while … Read more

The Role of Chirality in Drug Design and Delivery: A Comprehensive Review

  • Ashwini A. Aher
  • Syed Ubaid Razvi
  • Satish Eknath Bahekar
  • Mirza Shiraz Baig

Introduction The rotation of plane-polarized light by chiral substances was first observed in 1812 by a French physicist Jean-Baptiste Biot. Chiral chemistry was discovered by Louis Pasteur, a French chemist & biologist, in 1848 by inventing 2 isomers of sodium potassium tartrate (Fig. 1). The term chirality was coined in 1894 by Lord Kelvin, a … Read more

A Theoretical Understanding of Drug Abuse: Situational Analysis of Hyderabad

  • Syed Feroz Ahmed 1
  • Niloufar Azmi 1
  • Zeenathfar Azmi2

Introduction A theory is merely an explanation for a phenomenon that is applicable to a wide variety of situations and contexts. As such, the ideas covered in this chapter explain why people use and abuse substances under a range of diverse settings and circumstances.In the late 19th century, scientific inquiry into the problem of drug … Read more

Pelvic Congestion Syndrome: Etiology, Symptoms, and Epidemiology of a Chronic Pelvic Pain Disorder

  • Nida Ali Safdar
  • Soha Jabeen
  • Essra Ali Safdar

Introduction Chronic pelvic discomfort is a symptom of a disorder called pelvic congestion syndrome. It is believed to be brought on by issues with the pelvic veins. The lowest portion of your abdomen is this. The blood vessels that return blood to the heart are called veins. Veins in the lower abdomen may become dysfunctional … Read more

Zollinger-Ellison Syndrome: Causes, Symptoms, and Modern Approaches to Treatment

  • Nida Ali Safdar
  • Soha Jabeen
  • Essra Ali Safdar

Introduction Zollinger-Ellison Syndrome (ZES) is a rare but significant endocrine disorder characterized by the presence of gastrin-secreting tumors known as gastrinomas. These tumors lead to excessive production of gastric acid, resulting in severe gastrointestinal complications, including recurrent peptic ulcers and debilitating abdominal symptoms. First described in 1955 by Dr. Robert Zollinger and Dr. Edwin Ellison, … Read more

Exploring the Therapeutic Benefits of Honey: A Focus on Bioactive Compounds and Nutritional Composition

  • Tna Arunasree 1
  • Gyanendra Kumar2
  • Rohit Singh3

1. Introduction Honey, a natural product produced by bees from the nectar of flowers, has been cherished for centuries not only as a sweetener but also as a therapeutic agent. In many ancient cultures, honey was considered a sacred food, valued for its nutritional and medicinal properties. It has been used in traditional medicine systems, … Read more