Unani System of Medicine: Historical Evolution, Theoretical Foundations, Therapeutic Principles, and Contemporary Integration – A Comprehensive Review

1. Introduction The Unani System of Medicine (USM) also known as Graeco-Arabic Medicine, Unani Tibb, or Greco-Arab Medicine, is one of the oldest and most systematically developed traditional medical systems in human history, with its origins traceable to ancient Greece approximately 2,500–2,700 years ago [1,2].The word ‘Unani’ is derived from the Arabic transliteration of ‘Ionian’, … Read more

Nutraceuticals: A Paradigm Revolution in Medicine and Health

INTRODUCTION: World Health Organization (WHO) database on Global Health Expenditure, the United States allocated 17% of its resources towards healthcare, whereas India allocated 4% (WHO Indicators). The substantial expenditure on wellness has influenced the attention of both the research and development divisions of global corporations and customers towards food products that offer health advantages.[1]The “Nutraceutical” … Read more

A review of the pathophysiology of Alzheimer disease and their therapeutic strategies

Alzheimer’s disease (AD) is the leading cause of dementia in older adults, marked by progressive neurodegenerative alterations that affect the brain across different stages of the disease 1. Neuronal and synaptic degeneration in the cerebral cortex and specific subcortical regions is a hallmark of AD, leading to pronounced atrophy in regions such ascingulate gyrus, frontal … Read more

Mechanism of Endothelial Dysfunction in Hypertension: Nanotechnology-Based Interventions

Introduction Hypertension affects approximately 1.4 billion individuals globally and remains a major risk factor for cardiovascular diseases, which are now the leading cause of mortality worldwide [1]. A central pathological feature of hypertension is endothelial dysfunction, which is marked by impaired vasodilation, increased vasoconstriction, cellular proliferation, and a shift toward a proinflammatory and prothrombotic state … Read more

Bioactive Peptides from Fermented Foods as Natural Antimicrobials and Antioxidants

Introduction Fermented foods have emerged as a promising source of bioactive peptides (BAPs) that demonstrate significant antimicrobial and antioxidant properties, offering sustainable alternatives to synthetic preservatives and therapeutic agents [1]. BAPs are peptides consisting of 2 to 20 amino acids originating from precursor proteins following an activation process involving multiple reactions such as chemical hydrolysis, … Read more

Understanding the Therapeutic Versatility of Apigenin and Quercetin: Broad Applications in Health and Wellness

Introduction Flavonoids are quite an important class of natural substances. Specifically, these are a type of secondary metabolic by-products from crops that have a polyphenolic framework as well as are frequently found in vegetables, fruits, and some beverages [1]. These substances provide plants with adefense against diseases, UV rays, and herbivores [2]. Anthocyanins, flavones, flavanols, … Read more

The Role of Chirality in Drug Design and Delivery: A Comprehensive Review

Introduction The rotation of plane-polarized light by chiral substances was first observed in 1812 by a French physicist Jean-Baptiste Biot. Chiral chemistry was discovered by Louis Pasteur, a French chemist & biologist, in 1848 by inventing 2 isomers of sodium potassium tartrate (Fig. 1). The term chirality was coined in 1894 by Lord Kelvin, a … Read more

Exploring the Therapeutic Benefits of Honey: A Focus on Bioactive Compounds and Nutritional Composition

1. Introduction Honey, a natural product produced by bees from the nectar of flowers, has been cherished for centuries not only as a sweetener but also as a therapeutic agent. In many ancient cultures, honey was considered a sacred food, valued for its nutritional and medicinal properties. It has been used in traditional medicine systems, … Read more

Is Vitamin B17 Quackery or a Cancer Cure? An Extensive Analysis

INTRODUCTION One of the biggest issues facing both industrialized and emerging nations is the spread of diseases linked to modern civilization. The advancement of technology and the consequent contamination of the environment have been linked to a rise in diseases like diabetes, cancer, osteoporosis, obesity, cardiovascular disease, neurological disorders, and autoimmune diseases [1]. A group … Read more

Bionics in Medicine: The Future of Organ Replacement

Introduction In the ever-evolving landscape of medical science, the integration of bionics stands as a beacon of hope and innovation. Bionics, a term coined from the fusion of biology and electronics, refers to the study and design of systems inspired by biological processes. This field, especially in the context of medicine, has the potential to … Read more