Article Archive: Volume 4 Issue 1 2025

Evaluation of the protective role of the seed coat of Caesalpinia bonduc L.Roxb. against chronic fatigue syndrome induced by forced swimming in rats

  • Mohamed Aaqib
  • Abubaker Siddiq
  • Nataraj GR
  • Gagana D

Introduction Fatigue is one of the most common symptoms encountered in both clinical and community settings. In most individuals, fatigue is transient, self-limiting, and attributable to identifiable circumstances such as physical exertion, emotional stress, or acute illness. However, a subset of individuals experience persistent and debilitating fatigue that is not relieved by rest and cannot … Read more

Encapsulation of synbiotics & assessment of survival ability to various physiological stresses

  • Prarthana J 1
  • Shraddha2

Introduction The popularity of functional foods is increasing steadily over the period of time. Functional food offers personal health benefits due to bioactive microbial cells, as probioticimprove in maintaining gut microbiota, harnessing prevention or curing of illness[1]. A vast population of micro organisms thrives in human gastro intestinal tract, forming gut microbiota. Approximately 1010-1012 live … Read more

A review of the pathophysiology of Alzheimer disease and their therapeutic strategies

  • Chetehouna Sara1
  • Atoussi Ouidad1
  • Derouiche Samir1,2

Alzheimer’s disease (AD) is the leading cause of dementia in older adults, marked by progressive neurodegenerative alterations that affect the brain across different stages of the disease 1. Neuronal and synaptic degeneration in the cerebral cortex and specific subcortical regions is a hallmark of AD, leading to pronounced atrophy in regions such ascingulate gyrus, frontal … Read more

Antimicrobial, Wound healing and Anti mutagenic Activity of Momordica charantia Leaves Extract

  • Agrawal, R.
  • Srivastava, T.

1. INTRODUCTION  Karela [ Momordica charantia ,family Cucurbitaceous] , It isa popular vegetable that is widely grown in tropical areas., It has been reported to have multiple influences on glucose and lipid metabolism [1,2].It has demonstrated activity against Helicobacter pylori[the stomach ulcer-causing bacteria].It has showed  resistance to viral infections and had an immunostimulant effect in humans … Read more

Redesigning of Habb e Adrak into Lozenges along with its Pharmaceutical Analysis

  • Aziz ur Rahman1
  • Nusrat1
  • Huda Nafees1
  • Qazi Zaid Ahmad1
  • Muhammed Nadeem Khan2

Introduction Today, a large number of people around the world depend on herbal medicines to manage their basic health needs. Treatments made from medicinal plants are generally considered safe because they have few or no side effects. A major advantage of herbal medicines is that they can be used by people of all age groups … Read more

Mechanism of Endothelial Dysfunction in Hypertension: Nanotechnology-Based Interventions

  • Javeria Zaheer1,2

Introduction Hypertension affects approximately 1.4 billion individuals globally and remains a major risk factor for cardiovascular diseases, which are now the leading cause of mortality worldwide [1]. A central pathological feature of hypertension is endothelial dysfunction, which is marked by impaired vasodilation, increased vasoconstriction, cellular proliferation, and a shift toward a proinflammatory and prothrombotic state … Read more

Bioactive Peptides from Fermented Foods as Natural Antimicrobials and Antioxidants

  • Harshita

Introduction Fermented foods have emerged as a promising source of bioactive peptides (BAPs) that demonstrate significant antimicrobial and antioxidant properties, offering sustainable alternatives to synthetic preservatives and therapeutic agents [1]. BAPs are peptides consisting of 2 to 20 amino acids originating from precursor proteins following an activation process involving multiple reactions such as chemical hydrolysis, … Read more

Assessment of Anthelmintic Activity of Cinnamic Acid and Its Three Analogs: a Combined in Vitro and in Silico Study

  • Sheeba Baby Alex1,2
  • Ullas Mohan1
  • M. S.Latha2

INTRODUCTION Parasitic worms, known as helminths, are a significant source of public health concern due to their widespread occurrence in both human and animal populations, resulting in a high incidence of infection.Helminth infections are estimated to affect approximately a quarter of the world’s population.Helminths are unique among parasites because they multiply inside the definitive host … Read more

Understanding the Therapeutic Versatility of Apigenin and Quercetin: Broad Applications in Health and Wellness

  • Priya Shetti
  • Shivangini Singh
  • Vijay Kumbar
  • Suneel Dodamani
  • Ramesh Paranjape
  • Mitali Kubade

Introduction Flavonoids are quite an important class of natural substances. Specifically, these are a type of secondary metabolic by-products from crops that have a polyphenolic framework as well as are frequently found in vegetables, fruits, and some beverages [1]. These substances provide plants with adefense against diseases, UV rays, and herbivores [2]. Anthocyanins, flavones, flavanols, … Read more